4ª Rodada - 25 e 26/08

Sunderland 0 x 2 Liverpool - Stadium of Light, Sunderland
(Sissoko 37' e Voronin 87')

Arsenal 1 x 0 Manchester City - Emirates Stadium, Londres
(Fabregas 80')

Chelsea 1 x 0 Portsmouth - Stamford Bridge, Londres
(Lampard 31')

Manchester United 1 x 0 Tottenham - Old Trafford, Manchester
(Nani 68')

West Ham 1 x 1 Wigan - Upton Park, Londres
(Bowyer 81'; Scherner 78')

Aston Villa 2 x 1 Fulham - Villa Park, Birmingham
(Knight(contra) 51' e Maloney 90'; Dempsey 6')

Bolton 3 x 0 Reading - Reebok Stadium, Bolton
(Speed 32', Anelka 55' e Braaten 90')

Derby County 1 x 2 Birmingham - Pride Park, Derby
(Oakley 51'; Jerome 1' e 63')

Middlesbrough 2 x 2 Newcastle - Riverside, Middlesbrough
(Mido 28' e 70'; N'Zogbia 22' e Viduka 67')

Everton 1 x 1 Blackburn - Goodison Park, Liverpool
(McFadden 77'; Roque Santa Cruz 14')